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Search Results for " interleukin 6 receptor "

Targets

15

Compounds

3

Natural Products

36

Recombinant Proteins

Cat No. Product Name Synonyms Targets
TP1422 Interleukin (IL)-6 Receptor Others
Interleukin (IL)-6 Receptor is a peptide.
T5110 IRAK inhibitor 6 IRAK
IRAK inhibitor 6 is an inhibitor of interleukin-1 receptor-associated kinase 4 (IRAK-4, IC50: 160 nM).
T12352 Oxidopamine hydrochloride 6-Hydroxydopamine hydrochloride,6-OHDA hydrochloride Mitophagy , Dopamine Receptor , Autophagy
Oxidopamine hydrochloride (6-Hydroxydopamine hydrochloride) is an neurotransmitter dopamine antagonist.
T12352L Oxidopamine hydrobromide 6-Hydroxydopamine hydrobromide,6-OHDA hydrobromide Mitophagy , Dopamine Receptor , Autophagy
Oxidopamine hydrobromide (6-OHDA hydrobromide) is a neurotransmitter dopamine antagonist.
TQ0181 Resatorvid CLI-095,TAK-242 TNF , TLR , Autophagy , Interleukin
Resatorvid (TAK-242) is a selective inhibitor of Toll-like receptor 4 (TLR4). Resatorvid binds directly to Cys747 and prevents TLR4 from binding to TIRAP, thereby blocking downstream signaling. Resatorvid has antitumor a...
T4602 Hydrocortisone hemisuccinate Hydrocortisone 21-he,hydrocortisone 21-hemisuccinate*free acid,Hydrocortisone 21-hemisuccinate Glucocorticoid Receptor , Others , Interleukin
Hydrocortisone hemisuccinate (hydrocortisone 21-hemisuccinate*free acid) is a corticosteroid used as an analytical and chromatography reagent.
T76722 Sarilumab REGN-88,SAR-153191 IL Receptor
Sarilumab (SAR-153191)is a potent interleukin-6 IL-6 receptor antagonist and a human immunoglobulin G1 monoclonal antibody. Sarilumab inhibits IL-6-mediated signaling and reduces inflammation.Sarilumab is used for the pr...
T9911 Tocilizumab Interleukin
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor
T12781 RV01 Others
RV01 is a novel quinoline-substituted analogue of resveratrol that inhibits DNA damage, reduces ethanol-induced acetaldehyde dehydrogenase (ALDH2) mRNA expression, and has hydroxyl radical scavenging activity. rV01 reduc...
T2548 Diflorasone Glucocorticoid Receptor
Diflorasone is a synthetic glucocorticoid with anti-inflammatory and immunosuppressive properties. Like other glucocorticoids, diflorasone enters the cell by diffusion across the cell membrane and binds to the glucocorti...
T39903 PROTAC IRAK4 degrader-6 PROTAC IRAK4 degrader-6
PROTAC IRAK4 degrader-6 is a potent Cereblon-based compound designed to degrade interleukin-1 receptor-associated kinase 4 (IRAK4).
T34811 Terrein NSC 291308,Terrain,(+)Terrein,NSC291308,NSC-291308
Terrain, also known as NSC 291308, is a fungal metabolite with diverse biological activities. Terrein reduces age-related inflammation induced by oxidative stress through Nrf2/ERK1/2/HO-1 signalling in aged HDF cells. (+...
T77062 Levilimab
Levilimab (BCD-089), a fully human monoclonal antibody targeting the interleukin-6 receptor (IL-6R), serves as an inflammation-reducing agent. This compound is utilized in the study of rheumatoid arthritis [1].
T73372 GNE-2256
GNE-2256, also known as molecule 19, is an orally active compound that inhibits Interleukin 1 receptor-associated kinase 4 (IRAK4) with a K i of 1.4 nM and has an IL-6 inhibition concentration (IC50) of 190 nM.
T37604 ITK inhibitor
Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine recept...
Cat No. Product Name Synonyms Targets
T2758 Madecassic acid 6-Deoxy-L-Galactose,L-Fucose,Brahmic acid,L-fucopyranose Others , TNF , COX , NO Synthase , Interleukin
Madecassic acid (L-fucopyranose) is extracted from the whole herb of Centella asiatica.
T2893 Muscone 3-Methylcyclopentadecanone,Methylexaltone MMP , TNF , NF-κB , NOD-like Receptor (NLR) , P-gp , Interleukin
Muscone (3-Methylcyclopentadecanone) is an organic compound that is the primary contributor to the odor of musk.
T0798 Triamcinolone Fluoxyprednisolone,Aristocort,Rodinolone Glucocorticoid Receptor , COX
Triamcinolone (Aristocort) is a synthetic glucocorticoid with anti-inflammatory and immunomodulating properties. Upon cell entry, triamcinolone binds to and activates the glucocorticoid receptor, which leads to transloca...

Recombinant Proteins

Cat No. Product Name Species Expression System
TMPY-01214 IL-6R Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
IL-6R Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39 kDa and the accession number is P22272.
TMPY-00864 IL-6R Protein, Human, Recombinant (His) Human HEK293 Cells
IL-6R Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is A0N0L5.
TMPY-05278 IL-6R Protein, Human, Recombinant (hFc) Human HEK293 Cells
IL-6R Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 65.3 kDa and the accession number is A0N0L5.
TMPY-04859 IL-6R Protein, Rhesus, Recombinant (His) Rhesus HEK293 Cells
IL-6R Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.6 kDa and the accession number is A0A5F8AUE5.
TMPY-04187 IL-6R Protein, Rat, Recombinant (hFc) Rat HEK293 Cells
IL-6R Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 64.8 kDa and the accession number is A6J6I0.
TMPY-00135 IL-6R Protein, Canine, Recombinant (His) Canine HEK293 Cells
IL-6R Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.8 kDa and the accession number is A0A8C0PF44.
TMPY-02560 IL-6R Protein, Rat, Recombinant (His) Rat HEK293 Cells
IL-6R Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 39.5 kDa and the accession number is A6J6I0.
TMPY-05559 IL-20RB Protein, Human, Recombinant (His) Human Baculovirus Insect Cells
IL-20RB Protein, Human, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 23.9 kDa and the accession number is Q6UXL0-1.
TMPJ-00194 IL-20RB Protein, Human, Recombinant (hFc) Human HEK293 Cells
Interleukin-20 receptor subunit beta(IL20RB) is a single-pass type I membrane protein and belongs to the type II cytokine receptor family. It contains 2 fibronectin type-III domains. There are two kinds of type II cytoki...
TMPY-06297 IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 41.80 kDa and the accession number is A0N0L5.
TMPY-05640 IL-6R Protein, Human, Recombinant, Biotinylated Human HEK293 Cells
IL-6R Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 67.1 kDa and the accession number is A0N0L5.
TMPJ-00291 IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated Human HEK293 Cells
Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. IL6Ra is a part of the receptor for interleukin 6 cytokine. IL6Ra binds to...
TMPJ-01467 Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His) Human E. coli
Oncostatin M (OSM) is a glycoprotein belonging to the interleukin-6 family of cytokines that includes leukemia-inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6. OSM encodes a growth regulator, ...
TMPK-00101 IL-6 Protein, Cynomolgus, Recombinant (His) Cynomolgus HEK293 Cells
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression.Interleukin 6 has been shown to interact with interleukin-6 recep...
TMPK-00289 IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
The multifunctional factor interleukin 6 (IL-6) exerts its activities through binding to a high-affinity receptor complex consisting of two membrane glycoproteins: an 80 kDa component receptor that binds IL-6 with low af...
TMPK-01096 IL-31RA Protein, Mouse, Recombinant (His) Mouse HEK293 Cells
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPK-01113 IL-31RA Protein, Human, Recombinant (aa 20-519, hFc) Human HEK293 Cells
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPK-01114 IL-31RA Protein, Human, Recombinant (aa 20-519, His) Human HEK293 Cells
Interleukin-31 receptor A (IL-31RA) is a newly identified type I cytokine receptor, that is related to gp130, the common receptor of the interleukin (IL) -6 family cytokines. IL-31RA forms a functional receptor complex f...
TMPK-00646 Gp130/IL6ST Protein, Rhesus macaque, Recombinant (His) Rhesus HEK293 Cells
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic fa...
TMPK-00412 Gp130/IL6ST Protein, Human, Recombinant (His) Human HEK293 Cells
gp130 is a common signal transducing component of the functional receptor complexes for the interleukin (IL)-6 family of cytokines, ie, IL-6, IL-11, leukemia inhibitory factor (LIF), oncostatin M, ciliary neurotrophic fa...
TMPJ-00397 IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
CD217, also known as Interleukin-17 receptor A, is a T cell expressed pleotropic cytokine with 866 amino acids in length. CD217 functions as receptors for IL17A and IL17F, it binds to IL17A with higher affinity than to I...
TMPJ-00047 IL-31 Protein, Human, Recombinant Human E. coli
Human Interleukin 31 (IL-31) is a cytokine containing a four-helix bundle structure. It shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. Human IL-31 cDNA encodes...
TMPY-04421 FES Protein, Human, Recombinant (His & GST) Human Baculovirus Insect Cells
Proto-oncogene tyrosine-protein kinase Fes/Fps, also known as Proto-oncogene c-Fes, Proto-oncogene c-Fps, Feline sarcoma oncogene, FES and FPS, is a protein which contains oneFCH domain, oneprotein kinase domain and o...
TMPY-05353 CCL26 Protein, Human, Recombinant Human Baculovirus Insect Cells
The eotaxin subfamily of CC chemokines consists of eotaxin-1/CCL11, eotaxin-2/CCL24 and eotaxin-3/CCL26. All eotaxins induce the trafficking of eosinophils to the sites of inflammation via CC chemokine receptor 3 (CCR3),...
TMPY-02705 NRG1 beta 1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 55.2 kDa and the accession number is Q02297-6.
TMPY-04277 CD45 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 71.7 kDa and the accession number is P06800-6.
TMPY-03010 NRG1 beta 1 Protein, Human, Recombinant Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 26.8 kDa and the accession number is Q02297-6.
TMPJ-00827 Tau-D Protein, Human, Recombinant (His) Human E. coli
Microtubule-Associated Protein TAU is abundantly expressed in neurons of the central nervous system and less commonly expressed elsewhere, but is also expressed at very low levels in CNS astrocytes and oligodendrocytes. ...
TMPK-00614 NKp46/NCR1 Protein, Human, Recombinant (His) Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPJ-00567 NCR1 Protein, Human, Recombinant (hFc) Human HEK293 Cells
Natural cytotoxicity triggering receptor 1(NCR1) is a single-pass type I membrane protein .It contains 2 Ig-like (immunoglobulin-like) domains and belongs to the natural cytotoxicity receptor (NCR) family. The protein is...
TMPY-03128 LAIR1 Protein, Mouse, Recombinant (hFc) Mouse HEK293 Cells
LAIR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 39.6 kDa and the accession number is Q8BG84-6.
TMPK-00615 NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated Human HEK293 Cells
NKp46, along with NKp30 and NKp44, are activating receptors that have been collectively termed the natural cytotoxicity receptors (NCR).These receptors lack significant sequence homology to one another. They are expresse...
TMPY-02600 NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) Human HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc) is expressed in HEK293 mammalian cells with Fc tag. The predicted molecular weight is 36.7 kDa and the accession number is Q02297-6.
TMPY-05798 VEGF145 Protein, Human, Recombinant Human HEK293 Cells
VEGF145 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 16.92 kDa and the accession number is P15692-6.
TMPK-01364 SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
TMPK-01358 SIRP alpha V6 Protein, Human, Recombinant (His & Avi) Human HEK293 Cells
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadl...
IL-6R Protein, Mouse, Recombinant (His)
TMPY-01214
Species: Mouse
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant (His)
TMPY-00864
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant (hFc)
TMPY-05278
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Rhesus, Recombinant (His)
TMPY-04859
Species: Rhesus
Expression System: HEK293 Cells
IL-6R Protein, Rat, Recombinant (hFc)
TMPY-04187
Species: Rat
Expression System: HEK293 Cells
IL-6R Protein, Canine, Recombinant (His)
TMPY-00135
Species: Canine
Expression System: HEK293 Cells
IL-6R Protein, Rat, Recombinant (His)
TMPY-02560
Species: Rat
Expression System: HEK293 Cells
IL-20RB Protein, Human, Recombinant (His)
TMPY-05559
Species: Human
Expression System: Baculovirus Insect Cells
IL-20RB Protein, Human, Recombinant (hFc)
TMPJ-00194
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant (His & Avi), Biotinylated
TMPY-06297
Species: Human
Expression System: HEK293 Cells
IL-6R Protein, Human, Recombinant, Biotinylated
TMPY-05640
Species: Human
Expression System: HEK293 Cells
IL-6R alpha/CD126 Protein, Human, Recombinant (Avi & His), Biotinylated
TMPJ-00291
Species: Human
Expression System: HEK293 Cells
Oncostatin M/OSM Protein, Human, Recombinant (E. coli, His)
TMPJ-01467
Species: Human
Expression System: E. coli
IL-6 Protein, Cynomolgus, Recombinant (His)
TMPK-00101
Species: Cynomolgus
Expression System: HEK293 Cells
IL-6R alpha/CD126 Protein, Human, Recombinant (His & Avi)
TMPK-00289
Species: Human
Expression System: HEK293 Cells
IL-31RA Protein, Mouse, Recombinant (His)
TMPK-01096
Species: Mouse
Expression System: HEK293 Cells
IL-31RA Protein, Human, Recombinant (aa 20-519, hFc)
TMPK-01113
Species: Human
Expression System: HEK293 Cells
IL-31RA Protein, Human, Recombinant (aa 20-519, His)
TMPK-01114
Species: Human
Expression System: HEK293 Cells
gp130/IL6ST Protein, Rhesus macaque, Recombinant (His)
TMPK-00646
Species: Rhesus
Expression System: HEK293 Cells
gp130/IL6ST Protein, Human, Recombinant (His)
TMPK-00412
Species: Human
Expression System: HEK293 Cells
IL-17RA Protein, Human, Recombinant (His & Avi), Biotinylated
TMPJ-00397
Species: Human
Expression System: HEK293 Cells
IL-31 Protein, Human, Recombinant
TMPJ-00047
Species: Human
Expression System: E. coli
FES Protein, Human, Recombinant (His & GST)
TMPY-04421
Species: Human
Expression System: Baculovirus Insect Cells
CCL26 Protein, Human, Recombinant
TMPY-05353
Species: Human
Expression System: Baculovirus Insect Cells
NRG1 beta 1 Protein, Human, Recombinant (hFc)
TMPY-02705
Species: Human
Expression System: HEK293 Cells
CD45 Protein, Mouse, Recombinant (hFc)
TMPY-04277
Species: Mouse
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant
TMPY-03010
Species: Human
Expression System: HEK293 Cells
Tau-D Protein, Human, Recombinant (His)
TMPJ-00827
Species: Human
Expression System: E. coli
NKp46/NCR1 Protein, Human, Recombinant (His)
TMPK-00614
Species: Human
Expression System: HEK293 Cells
NCR1 Protein, Human, Recombinant (hFc)
TMPJ-00567
Species: Human
Expression System: HEK293 Cells
LAIR1 Protein, Mouse, Recombinant (hFc)
TMPY-03128
Species: Mouse
Expression System: HEK293 Cells
NKp46/NCR1 Protein (Primary Amine Labeling), Human, Recombinant (His), Biotinylated
TMPK-00615
Species: Human
Expression System: HEK293 Cells
NRG1 beta 1 Protein, Human, Recombinant (EGF Domain, hFc)
TMPY-02600
Species: Human
Expression System: HEK293 Cells
VEGF145 Protein, Human, Recombinant
TMPY-05798
Species: Human
Expression System: HEK293 Cells
SIRP alpha V6 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-01364
Species: Human
Expression System: HEK293 Cells
SIRP alpha V6 Protein, Human, Recombinant (His & Avi)
TMPK-01358
Species: Human
Expression System: HEK293 Cells
TargetMol